Again,
Why IGF-1 is more expensive than HGH? Because most people respond well to HGH therapy.
RH IGF-1 is created for those who don't respond well to HGH therapy and who need higher(normal) systemic IGF-1 levels throughout the day. The key words are SYSTEMIC and THROUGHOUT THE DAY. This way kids with open growth plates have IGF-1 in their bloodstream most of the time.
Let's look at Iplex, it comes with IGFBP3 in the mix (IGF-1 + IGFBP3). It's created for those with LOW IGFBP3 levels.
Increlex/RH IGF-1 isn't not prescribed for HRT/TRT. Why? Because it's pricey and adult men don't need lineal growth (growth plates are closed) and medicine don't really care if you wanna look jacked.
HOW and WHY athletes benefit from just 200 mcg/day when kids need MILIGRAMS? Kids need higher dosages so more IGF-1 will bound to it's binding proteins and will stay in the bloodstream longer WHEN athletes need 200 mcg of FREE aka BIOACTIVE IGF-1 to feed it's muscles (our muscles have IGF-1 receptors). Athletes don't chase lineal growth, they want performance enhancement.
With IGF-1 you get mostly FREE/BIOACTIVE IGF-1, that's what athlete pay for, they don't pay for higher total/systemic IGF-1 levels.
You refer to Palumbo. Palumbo was selling IGF-1 reagents (LR3/DES), those 2 won't even be detected as IGF-1 on a bloodwork, the use of this reagents by athletes is pure broscience with no scientific data.
You want higher Systemic levels of IGF-1? Google Increlex dosing and follow it's dosing protocols, which is MG"s a day. If you won't respond well to RH IGF-1 then your body doesn't release IGF-1 binding proteins and you need Iplex.
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"How did you like the Qtropin? That was the same company that I got my bogus IGF from?" - You posted this on MESO, you discredit us and our products for no reason, if someone takes Testosterone and expect his penis to grow 5 inches and blames the product and not his ignorance for the failed expectations, that's not our fault. After I posted all the info here and emailed you, you went on MESO called our IGF-1 bogus? You can try to get a script for Increlex, you won't get it from here.
RS
mt wrote:
Administrator wrote:
@ mt, Why kids use Increlex instead of HGH? The reason is some kids with low HGH levels can't convert HGH to IGF-1 effectively, so they inject IGF-1 directly. When you inject IGF-1 it will bound to it's binding proteins (see my previous post) and it will circulate in your bloodstream BOUND to this proteins. In order to have higher systemic IGF-1 level you need to follow the same dosing protocol (the one kids follow) and kids inject MILIGRAMS of IGF-1 /day. If someone told me : RS, I wanna have higher IGF-1 levels and I don't respond well to HGH therapy, I'd tell to inject IGF-1 1-2mg/day for a few weeks and then do the test and re-assess the dosage. Most athletes get good results from just 200 mcg/day, as it's pharmacokinetics is different from HGH and IGF-1 from HGH therapy.
Then, in order to see how you respond to IGF-1, you need to stop HGH for a few weeks completely, do bloodwork, start IGF-1 and re-test after 2 weeks. This way your experiment with 100-200 mcg/day would be legit, but still, expecting huge increase in total IGF-1 from 100 mcg/day shouldn't be expected.
Well, I arrived at my dosing protocol the same way we all do. I research the product, got multiple points of view, piggy-backed on vets with real-world hands-on experience. Dave Palumbo recommended 50 mcg/day. Now whatever he says to take or what he took on a public forum like YouTube I just triple the amount. I came to the conclusion that the dosages range from 50-200 mcg. I started at 50 mcg for about five days just to make sure I didn't have any adverse reaction. Then 100 mcg/day for the rest of the four week cycle.
I already established a baseline IGF level after being off HGH for over a year. It came in at a dismal 53 ng/ml. I experimented with various suppliers and brands. I used TheProvider mostly and used his Mauves, Black Tops, and Grey Tops which I believe is the same as Opti's "120iu kit". I decided to go for broke and for six weeks took 15-20ius of TP's Black Tops. My IGF level didn't go past 160 ng/ml. My state doesn't allow an HGH serum test without a script so I sent a vial to another member who did an HGH serum test. It was not the advertised 15 ius/vial but it did contain HGH. I finally convince my doctor to write me a script to get a Serum test. I tested 10ius of Opti's Purple Tops which he claimed was 24 ius/vial and selling it as 240 iu kits. I chose that brand instead of the Greys, which I normally use because I'm very skeptical about all these high dosed claims.
I used the standard protocol of 10ius 3 hours before having blood drawn. Well, that "cheap" GH came in at over 34 ng/ml. That's when I was sure that the problem was with me and my ability to convert IGF. I was taking 8 ius/day for a month of the Purple Tops prior to testing.
After that, I was back to my normal dosage of 6ius/day of the Grey tops which kept me at around the 160 range IGF levels. When starting your IGF product I cut my GH dosage to 4ius/day due to running out of stock. As you can see by my test results my IGF level dropped to the 90s. Over a 40% drop just by dropping my HGH dose by 2 ius. I had thought, hoped, that your product would have picked up the slack but it seems to have done nothing at all.
I will take your advice and up the dose to 500 mcg/day. In all my research I haven't read of anybody going that high but I really, really want this to work. I'm not trying to bring anybody or any company down and I have no affiliation with any of your competitors. I chose you because I am on the Meso site where Qore advertises, and they seem to have the cleanest and most professional presentation. They are not some college kid brewing gear out of his kitchen sink. I got two vials from you and that would mean a single vial will now last me just 20 days. I still have some from the first vial which I began today with 150 mcg after taking 19 days off. I won't have enough for a five-week or even a four-week cycle but hopefully, after three weeks I will be able to get a good idea of my response when I send in another blood sample. I don't want to invest even more money on a product that doesn't work for me. I'm just an average working stiff like most here and we don't have a lot of extra ching to burn.
I'm going to pin another 350 mcg to add to the 150 I took earlier today after I send this out to get my dosage to 500 mcg. And I thought 10 clicks on the slin pin burned. Doing a half a cc is really going to be fun
